chercheur | University Abu Bekr Belkaid | Algeria
Prof. Dr. Ghalem Saïd is a distinguished researcher at Université Abou Bekr Belkaid Tlemcen, Algeria, recognized for his extensive contributions to medicinal chemistry, natural product bioactivity, computational modeling, and molecular pharmacology. With a strong publication record of 53 scientific documents and over 1,083 citations from 1,011 citing sources, he has established a solid international footprint in interdisciplinary research at the interface of biology, chemistry, and pharmaceutical sciences. His work spans in vitro, in vivo, and in silico methodologies, with notable studies on bioactive compounds from medicinal plants, enzyme inhibition, drug discovery, and structure-based molecular modeling. Recent publications include integrated discovery approaches for pancreatic lipase inhibitors from Corchorus olitorius, computational analysis of xanthine oxidase inhibition relevant to gout therapy, and investigations into the insecticidal and bactericidal activities of Cassia nigricans. His research also extends to molecular docking and pharmacophore evaluation, particularly in the context of SARS-CoV 3CL protease inhibitor discovery, exemplifying his engagement with global health challenges and antiviral drug repurposing. With an h-index of 17, Prof. Dr. Ghalem demonstrates consistent scholarly influence supported by collaborations with over 117 co-authors across diverse institutions and disciplines. His work not only advances theoretical and computational chemistry but also drives translational applications in therapeutics, agrochemical innovation, and disease management. Through his commitment to rigorous scientific inquiry, multidisciplinary integration, and societal relevance, Prof. Dr. Ghalem Saïd continues to contribute meaningfully to international research efforts aimed at developing safer, more effective bioactive agents and strengthening the scientific foundations of medicinal plant valorization and modern drug discovery.
Featured Publications
1. Larabi, L., Harek, Y., Benali, O., & Ghalem, S. (2005). Hydrazide derivatives as corrosion inhibitors for mild steel in 1 M HCl. Progress in Organic Coatings, 54(3), 256–262.
Cited by: 243
2. Abdelli, I., Hassani, F., Bekkel Brikci, S., & Ghalem, S. (2021). In silico study of the inhibition of angiotensin-converting enzyme 2 receptor of COVID-19 by Ammoides verticillata components harvested from Western Algeria. Journal of Biomolecular Structure and Dynamics, 39(9), 3263–3276.
Cited by: 237
3. Allali, H., Benmehdi, H., Dib, M. A., Tabti, B., Ghalem, S., & Benabadji, N. (2008). Phytotherapy of diabetes in West Algeria. Asian Journal of Chemistry, 20(4), 2701–2708.
Cited by: 184
4. Daoud, I., Melkemi, N., Salah, T., & Ghalem, S. (2018). Combined QSAR, molecular docking, and molecular dynamics study on new acetylcholinesterase and butyrylcholinesterase inhibitors. Computational Biology and Chemistry, 74, 304–326.
Cited by: 104
5. Amatore, C., Bensalem, S., Ghalem, S., & Jutand, A. (2004). Mechanism of the carbopalladation of alkynes by aryl-palladium complexes. Journal of Organometallic Chemistry, 689(24), 4642–4646.
Cited by: 100
Prof. Dr. Ghalem Saïd advances global scientific innovation through cutting-edge research in computational chemistry, natural product pharmacology, and molecular modeling, driving the discovery of novel therapeutics from bioactive plant compounds. His interdisciplinary work bridges in silico, in vitro, and in vivo approaches, contributing valuable insights to drug discovery, public health, and sustainable biomedical solutions.